Difficulties scaling proteomic studies have stifled its potential. But Encodia’s ProteoCode™ changes everything.
Our groundbreaking technology reverse translates peptide sequence information into a DNA library. This means scientists can scale their research more easily to accelerate novel approaches to our most challenging diseases.
Our technology reverse translates peptide sequence information into a DNA library. This means scientists can scale their research more easily to accelerate novel approaches to our most challenging diseases.
Affinity reagent binders with DNA barcode tags are introduced to the peptide-DNA chimera molecules. The identity of the affinity reagent is recorded when the DNA barcode tag binds to the peptide-DNA chimera.
After the affinity reagent tags bind to the DNA-peptide chimera, the ending amino acid is removed. This process is repeated for n-cycles to effectively sequence n-amino acids.
The result is a collection of billions of library elements, where each DNA barcode identifies an amino acid in the peptide.